منابع مشابه
Improved serodiagnosis of Lyme disease.
Aims-To determine whether enzyme linked immunosorbent assay (ELISA) results for Borrelia burgdorferi require confirmation by immunoblotting and how immunoblotting may best be used in the diagnosis of Lyme disease.Methods-Over one year, all referrals for Lyme disease to a district general hospital with a large tick population in its catchment area were tested by ELISA. Positive, low positive and...
متن کاملImmunoblot interpretation criteria for serodiagnosis of early Lyme disease.
We monitored the antibody responses of 55 treated patients with early Lyme disease and physician-documented erythema migrans. Six sequential serum samples were obtained from patients before, during, and until one year after antibiotic therapy and analyzed by in-house enzyme-linked immunosorbent (ELISA) and immunoblot assays. An immunoblot procedure utilizing a gradient gel and an image analysis...
متن کاملa case of lyme disease (lyme borreliosis)
while an important infectious disease in the united states and eurasia, lyme disease is rare in iran. we present a 9-year old boy admitted in children’s medical center in december 2001 with final diagnosis of lyme disease. on admission he showed arthritis and a history of previous skin lesions. serologic examination including enzyme–linked immunosorbent assay and western blot was positive for l...
متن کاملReport of a case of Lyme disease in Mazandaran
Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized stage of erythema chronicum migrans. The diagnosis was confirmed by the presence of se...
متن کاملRecombinant assay for serodiagnosis of Lyme disease regardless of OspA vaccination status.
All current seroassays using cultured Borrelia burgdorferi as their antigen source have been rendered obsolete by the recombinant OspA Lyme disease vaccine. OspA is the major outer surface protein expressed in cultured B. burgdorferi, and any seroassay that uses whole organisms as its antigen source cannot differentiate between subjects who received the vaccine and those who were naturally infe...
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ژورنال
عنوان ژورنال: Molecular Pathology
سال: 1996
ISSN: 1366-8714
DOI: 10.1136/mp.49.2.m80